The Pittsburgh Vaccination Research Group

Protecting People Vaccine Policy to Practice

Influenza Vaccine Immunogenicity Project

Funding Source: 
Project Dates: 
Thursday, April 2, 2015
Project Staff: 

The PittVax team has undertaken influenza immunogenicity studies which vary by vaccine type and target population.  The team has compared the immunological response to high dose vaccine vs. standard dose vaccine among frail elderly residents of nursing homes.  They have followed a cohort of middle aged and older community dwelling adults for several years, examining immunological response to annual seasonal influenza vaccine.  Among this cohort they have examined immunological response to historical influenza vaccine strains.  Another study is underway comparing immunological response to LAIV or IIV influenza vaccine among children 3-17 years of age who received no vaccine, LAIV or IIV in the previous season.  (See publications tab.)